Gert-Jan Both
Machine Learning Researcher II · HHMI Janelia Research Campus
I build AI systems and scientific software at the intersection of physics, biology, and ML — currently as a Machine Learning Researcher at HHMI Janelia Research Campus.
My work focuses on two threads: biomechanical foundation models for inferring neural activity across the connectome in Drosophila, and physics-based reconstruction pipelines for X-ray nano-holotomography. Both projects involve building novel computational tools that combine deep domain knowledge with modern ML — JAX, differentiable simulation, reinforcement learning, and large-scale GPU computing.
I build my tools in close collaboration with experimentalists and they frequently end up as open-source software.
Before Janelia, I spent time in industry as a Research Scientist at PASQAL, building computational tools across quantum simulation, hardware control, and AI — including GPU-accelerated quantum circuit simulators and holographic atom-trapping software.